Brain Radiation therapy has long term side effects particularly in young people

People with low grade cancer of brain have a prognosis of many years.

Hence, it is important from a quality of life point of view that alternative treatments are used to minimise or avoid the risk of brain damage from radiation

Vorasidenib is a new type of medical treatment . It is a tablet developed specifically to target a specific vulnerable part of low grade brain cancers. The Vorasidenib tablets target abnormal proteins in cancer and hence spares a lot of normal tissues.

A study presented at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago on June 4 is very promising.

Preliminary results show that the tablet significantly delays the growth of the tumour.

References

1. National Cancer Institute. Vorasidenib Treatment Shows Promise for Some Low-Grade Gliomas.

2. NEJM. Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma

3. Vorasidenib ASCO2023 news. INDIGO: Vorasidenib Offers Patients With IDH-Mutant Low-Grade Glioma a Means to Delay Chemotherapy and Radiotherapy

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